Inborn Errors of Metabolism (IEM)
Inborn errors of metabolism (IEM) are a genetically heterogeneous group of disorders caused by a defect in a metabolic pathway, leading to malfunctioning metabolism and the accumulation of toxic intermediate metabolites.
NeoMass AAAC Plus
Provides tandem mass spectrometry assay for quantitative measurement of amino acids, free carnitine, acylcarnitine, argininosuccinic acid, and succinyl acetone from Dried Blood Spot.
Features:
- A non-derivatized LC-MS/MS kit for the screening of 15 amino acids within a single LC-MS/MS run.
- Simple and time-saving sample extraction protocol within 1 hour for all analytes including SUAC without the use of any carcinogenic derivatization compound.
- Suitable for most mid- and high-sensitive LC-MS/MS instruments with analysis times of approximately 3 hours per plate (96 wells).
NeoMass AAAC 3.0
Is an upgraded version of NeoMass AAAC Plus with no changes to the extraction process, an addition of Nucleoside and lysophospholipid to detect adenosine deaminase (ADA) and X-linked adrenoleukodystrophy (X-ALD) genetic disorders with higher sensitivity and specificity.
Features:
- Screening of multiple disorders (>50 Disorders) with a single-run protocol.
- No use of any carcinogenic derivatization compound.
- Internal standards validated for long-term stability.
- Suitable for most mid- and high-sensitive LC-MS/MS instruments with analysis times of approximately 3 hours per plate (96 wells).
- Three levels of dried blood spots controls covering the clinically relevant range.
Inborn Errors of Metabolism (IEM)
Inborn errors of metabolism (IEM) are a genetically heterogeneous group of disorders caused by a defect in a metabolic pathway, leading to malfunctioning metabolism and the accumulation of toxic intermediate metabolites.
NeoMass AAAC Plus
Provides tandem mass spectrometry assay for quantitative measurement of amino acids, free carnitine, acylcarnitine, argininosuccinic acid, and succinyl acetone from Dried Blood Spot.
Features:
- A non-derivatized LC-MS/MS kit for the screening of 15 amino acids within a single LC-MS/MS run.
- Simple and time-saving sample extraction protocol within 1 hour for all analytes including SUAC without the use of any carcinogenic derivatization compound.
- Suitable for most mid- and high-sensitive LC-MS/MS instruments with analysis times of approximately 3 hours per plate (96 wells).
NeoMass AAAC 3.0
Is an upgraded version of NeoMass AAAC Plus with no changes to the extraction process, an addition of Nucleoside and lysophospholipid to detect adenosine deaminase (ADA) and X-linked adrenoleukodystrophy (X-ALD) genetic disorders with higher sensitivity and specificity.
Features:
- Screening of multiple disorders (>50 Disorders) with a single-run protocol.
- No use of any carcinogenic derivatization compound.
- Internal standards validated for long-term stability.
- Suitable for most mid- and high-sensitive LC-MS/MS instruments with analysis times of approximately 3 hours per plate (96 wells).
- Three levels of dried blood spots controls covering the clinically relevant range.
